Dr. Alexandra Kroll

Dr. Alexandra Kroll


E-Mail KontaktTel. +41 58 765 5487
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FX E23
Überlandstrasse 133
CH-8600 Dübendorf

Aufgaben am Oekotoxzentrum

  • Planung, Betreuung und Durchführung angewandter Projekte im Bereich Risikobewertung 
  • Ableitung von Qualitätskriterien
  • Planung, Durchführung und Mitarbeit in Weiterbildungskursen


  • Risikobewertung für Mikroverunreinigungen in Gewässern
  • Umweltrisikobewertung von Arzneimitteln
  • Zulassung von Pflanzenschutzmitteln
  • Effekte von Nanopartikeln und Mikroplastik auf Organismen



Curriculum vitae

  • seit 2019

    Wissenschaftliche Mitarbeiterin im Bereich Risikobewertung am Oekotoxzentrum

  • 2016-2019

    Projektmanagerin im Bereich Umweltrisikobewertung bei GAB Consulting, Deutschland

  • 2010-2016

    SNSF Ambizione research fellow und Postdoc an der Eawag. Forschungsthemen: Charakterisierung mikrobieller Biofilme, Interaktionen von Biofilmen mit Nanopartikeln, Mikroplastikpartikeln und Pestiziden

  • 2010

    Wissenschaftliche Projektassistentin, CeNTech GmbH, Deutschland

  • 2006-2009

    Promotion, Universitätsklinikum Münster, Deutschland. Thema: Charakterisierung von technisch hergestellten (Nano)Partikeln und Auswirkungen auf Wirbeltier-Zelllinien 

  • 2005-2006

    Wissenschaftliche Assistentin, Institut des Sciences du Végétal (ISV), CNRS Ile-de-France Sud, Frankreich

  • 2003-2004

    Diplomarbeit in Pflanzenphysiologie, Universität Heidelberg, Deutschland. Thema: Salzinduktion der Genexpression bei Arabidopsis thaliana und Beta vulgaris


  • Casado‐Martinez, M. C., Dell'Ambrogio, G., Campiche, S., Kroll, A., Lauber, E., Marti‐Roura, M., … Ferrari, B. J. D. (2024). Incorporation of sediment‐ and soil‐specific aspects in the criteria for Reporting and Evaluating Ecotoxicity Data (CRED). Integrated Environmental Assessment and Management. doi.org/10.1002/ieam.4948 , Institutional Repository
  • Ilbeigi, K., Barata, C., Barbosa, J., Bertram, M. G., Caljon, G., Costi, M. P., … Bundschuh, M. (2024). Assessing environmental risks during the drug development process for parasitic vector-borne diseases: a critical reflection. ACS Infectious Diseases, 10(4), 1026-1033. doi.org/10.1021/acsinfecdis.4c00131 , Institutional Repository
  • Kroll, A., von der Ohe, P. C., Köhler, H. R., Sellier, O., & Junghans, M. (2024). Aquatic thresholds for ionisable substances, such as diclofenac, should consider pH-specific differences in uptake and toxicity. Science of the Total Environment, 908, 168222 (9 pp.). doi.org/10.1016/j.scitotenv.2023.168222 , Institutional Repository
  • Merbt, S. N., Kroll, A., Sgier, L., Tlili, A., Schirmer, K., & Behra, R. (2024). Fate and effects of microplastic particles in a periphyton-grazer system. Environmental Pollution, 347, 123798 (9 pp.). doi.org/10.1016/j.envpol.2024.123798 , Institutional Repository
  • Spycher, S., Kalf, D., Lahr, J., Gönczi, M., Lindström, B., Pace, E., … Kroll, A. (2024). Linking chemical surface water monitoring and pesticide regulation in selected European countries. Environmental Science and Pollution Research, 31, 43432-43450. doi.org/10.1007/s11356-024-33865-y , Institutional Repository
  • Wang, X., Li, Y., Kroll, A., & Mitrano, D. M. (2024). Differentiating microplastics from natural particles in aqueous suspensions using flow cytometry with machine learning. Environmental Science and Technology, 58(23), 10240-10251. doi.org/10.1021/acs.est.4c00304 , Institutional Repository
  • James, A., Kroll, A., & Minier, C. (2023). Towards a better consideration of endocrine disruption within the technical guidance for deriving environmental quality standards. Regulatory Toxicology and Pharmacology, 143, 105457 (8 pp.). doi.org/10.1016/j.yrtph.2023.105457 , Institutional Repository
  • Daouk, S., Doppler, T., Scheidegger, R., Kroll, A., Junghans, M., Moschet, C., & Singer, H. (2022). Insecticides dans les eaux de surface. Quels risques représentent les insecticides pyréthrinoïdes et organophosphorés en Suisse?. Aqua & Gas, 102(4), 58-66. , Institutional Repository
  • Guasch, H., Bernal, S., Bruno, D., Almroth, B. C., Cochero, J., Corcoll, N., … Martí, E. (2022). Interactions between microplastics and benthic biofilms in fluvial ecosystems: knowledge gaps and future trends. Freshwater Science, 41(3), 442-458. doi.org/10.1086/721472 , Institutional Repository
  • Merbt, S. N., Kroll, A., Tamminen, M., Rühs, P. A., Wagner, B., Sgier, L., … Behra, R. (2022). Influence of microplastics on microbial structure, function, and mechanical properties of stream periphyton. Frontiers in Environmental Science, 10, 928247 (17 pp.). doi.org/10.3389/fenvs.2022.928247 , Institutional Repository
  • Konschak, M., Zubrod, J. P., Duque Acosta, T. S., Bouchez, A., Kroll, A., Feckler, A., … Bundschuh, M. (2021). Herbicide-induced shifts in the periphyton community composition indirectly affect feeding activity and physiology of the gastropod grazer Physella acuta. Environmental Science and Technology, 55(21), 14699-14709. doi.org/10.1021/acs.est.1c01819 , Institutional Repository
  • Kroll, A., Kienle, C., Schäfer, A., & Aicher, L. (2021). Mikroplastik in der Umwelt. Eine Standortbestimmung. Aqua & Gas, 101(10), 88-95. , Institutional Repository
  • Sambalova, O., Thorwarth, K., Heeb, N. V., Bleiner, D., Zhang, Y., Borgschulte, A., & Kroll, A. (2018). Carboxylate functional groups mediate interaction with silver nanoparticles in biofilm matrix. ACS Omega, 3(1), 724-733. doi.org/10.1021/acsomega.7b00982 , Institutional Repository
  • Sgier, L., Merbt, S. N., Tlili, A., Kroll, A., & Zupanic, A. (2018). Characterization of aquatic biofilms with flow cytometry. Journal of Visualized Experiments (136), e57655 (9 pp.). doi.org/10.3791/57655 , Institutional Repository
  • Sgier, L., Behra, R., Schönenberger, R., Kroll, A., & Zupanic, A. (2018). Evaluation of phototrophic stream biofilms under stress: comparing traditional and novel ecotoxicological endpoints after exposure to diuron. Frontiers in Microbiology, 9, 2974 (11 pp.). doi.org/10.3389/fmicb.2018.02974 , Institutional Repository
  • Wagner, T., Kroll, A., Haramagatti, C. R., Lipinski, H. G., & Wiemann, M. (2017). Classification and segmentation of nanoparticle diffusion trajectories in cellular micro environments. PLoS One, 12(1), e0170165 (20 pp.). doi.org/10.1371/journal.pone.0170165 , Institutional Repository
  • Kroll, A., Matzke, M., Rybicki, M., Obert-Rauser, P., Burkart, C., Jurkschat, K., … Svendsen, C. (2016). Mixed messages from benthic microbial communities exposed to nanoparticulate and ionic silver: 3D structure picks up nano-specific effects, while EPS and traditional endpoints indicate a concentration-dependent impact of silver ions. Environmental Science and Pollution Research, 23(5), 4218-4234. doi.org/10.1007/s11356-015-4887-7 , Institutional Repository
  • Sgier, L., Freimann, R., Zupanic, A., & Kroll, A. (2016). Flow cytometry combined with viSNE for the analysis of microbial biofilms and detection of microplastics. Nature Communications, 7, 11587 (10 pp.). doi.org/10.1038/ncomms11587 , Institutional Repository
  • Taylor, C., Matzke, M., Kroll, A., Read, D. S., Svendsen, C., & Crossley, A. (2016). Toxic interactions of different silver forms with freshwater green algae and cyanobacteria and their effects on mechanistic endpoints and the production of extracellular polymeric substances. Environmental Science: Nano, 3(2), 396-408. doi.org/10.1039/c5en00183h , Institutional Repository
  • Wagner, T., Kroll, A., Wiemann, M., & Lipinski, H. G. (2016). Classification of nanoparticle diffusion processes in vital cells by a multifeature random forests approach: application to simulated data, darkfield and confocal laser scanning microscopy. In J. Popp, V. V. Tuchin, D. L. Matthews, & F. S. Pavone (Eds.), Proceedings of SPIE: Vol. 9887. Biophotonics: photonic solutions for better health care V (p. 988722 (9 pp.). doi.org/10.1117/12.2227499 , Institutional Repository
  • Braun, A., Boudoire, F., Bora, D. K., Faccio, G., Hu, Y., Kroll, A., … Wilson, S. T. (2015). Biological components and bioelectronic interfaces of water splitting photoelectrodes for solar hydrogen production. Chemistry: A European Journal, 21(11), 4188-4199. doi.org/10.1002/chem.201405123 , Institutional Repository
  • Kroll, A., Behra, R., Kaegi, R., & Sigg, L. (2014). Extracellular polymeric substances (EPS) of freshwater biofilms stabilize and modify CeO2 and Ag nanoparticles. PLoS One, 9(10), e110709 (16 pp.). doi.org/10.1371/journal.pone.0110709 , Institutional Repository
  • Kroll, A., Gietl, J. K., Wiesmüller, G. A., Günsel, A., Wohlleben, W., Schnekenburger, J., & Klemm, O. (2013). In vitro toxicology of ambient particulate matter: correlation of cellular effects with particle size and components. Environmental Toxicology, 28(2), 76-86. doi.org/10.1002/tox.20699 , Institutional Repository
  • Kroll, A., Kühnel, D., & Schirmer, K. (2013). Testing nanomaterial toxicity in unicellular eukaryotic algae and fish cell lines. In D. Armstrong & D. J. Bharali (Eds.), Methods in molecular biology: Vol. 1028. Oxidative stress and nanotechnology. Methods and protocols (pp. 165-195). doi.org/10.1007/978-1-62703-475-3_11 , Institutional Repository
  • Stewart, T. J., Traber, J., Kroll, A., Behra, R., & Sigg, L. (2013). Characterization of extracellular polymeric substances (EPS) from periphyton using liquid chromatography-organic carbon detection–organic nitrogen detection (LC-OCD-OND). Environmental Science and Pollution Research, 20(5), 3214-3223. doi.org/10.1007/s11356-012-1228-y , Institutional Repository
  • Kroll, A., Pillukat, M. H., Hahn, D., & Schnekenburger, J. (2012). Interference of engineered nanoparticles with in vitro toxicity assays. Archives of Toxicology, 86(7), 1123-1136. doi.org/10.1007/s00204-012-0837-z , Institutional Repository
  • Kroll, A. (2012). Nanobiology-convergence of disciplines inspires great applications. Cellular and Molecular Life Sciences, 69(3), 335-336. doi.org/10.1007/s00018-011-0851-y , Institutional Repository
  • Kroll, A., Dierker, C., Rommel, C., Hahn, D., Wohlleben, W., Schulze-Isfort, C., … Schnekenburger, J. (2011). Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays. Particle and Fibre Toxicology, 8(1), 9 (19 pp.). doi.org/10.1186/1743-8977-8-9 , Institutional Repository